X-Chromosome Inactivation: A Scientific Breakthrough

May 8, 2025

X-chromosome inactivation stands as a fascinating cellular phenomenon that predominantly occurs in females, where one of the two X chromosomes is silenced to prevent gene dosage imbalance with males, who carry only one.This crucial process, investigated by researchers such as Jeannie Lee at Harvard Medical School, has opened new doors in understanding genetic disorders linked to the X chromosome, including Fragile X Syndrome and Rett Syndrome.
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